Chronic myeloid leukemia with soft tissue infiltration : a case report

نویسندگان

  • Gaurav Goswami
  • Yumkhaibam S. Devi
  • Laishram J. Singh
چکیده

Seorang pasien laki-laki 27 tahun dengan leukemia mielositik kronik dengan pengobatan hidroksi urea yang tidak teratur, datang dengan keluhan benjolan di pangkal paha kiri disertai rasa nyeri tumpul. Pemeriksaan darah menunjukkan lekosit 125.000/mm3 dengan 13% metamielosit, 8% mielosit, 1% promielosit dan 3% sel batang. Biopsi aspirasi jarum halus menunjukkan sebagian besar sel mieloblas dan sebagian kecil promielosit. Pengobatan diteruskan dengan hidroksi urea 2 g/ hari dalam dosis terbagi, disertai allopurinol, basa dan minum yang banyak. Gejala hilang pelan-pelan setelah 2 bulan, dan benjolan hilang setelah 3,5 bulan. Hitung lekosit menjadi 38.400/mm3 dengan 1% promielosit dan mieloblas, dan 5% batang. Pembesaran hati berkurang tapi ukuran limpa tidak mengecil. Pengobatan diteruskan dengan hidroksiurea 2 g/hari, dan gejala tidak pernah muncul lagi sampai 9 bulan terakhir.

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تاریخ انتشار 2015